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KMID : 1190620150110020067
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Journal of the Korean Wound Care Society
2015 Volume.11 No. 2 p.67 ~ p.81
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Effects of Various Pectin/CMC Dressing Materials on Different Types of Wound Models
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:Cho In-Gook
:Yang Jung-Dug/:Lee Jeong-Woo/:Choi Kang-Young/:Chung Ho-Yun/:Cho Byung-Chae/:Kwon Joon-Hyun/:Jang Kyung-Min
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Abstract
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This study tested the efficacy of Pectin/CMC dressing materials with different pH and absorption degrees for 3 types of wound models. White rats were divided into 3 groups by wound model type: surgical, infected, and burn wounds. The rats were given 1 of 4 types of dressing with different pHs and absorption degrees. Assessments were made over time of the remaining wound and histological and biochemical tests. In fresh surgical wounds, Group A showed statistically lower contraction rate, lower healing rate, Group D showed statistically lower re-epithelization rate. In infected wounds, Group A and D showed better healing on 7th day, but Group B and C showed better healing on 21st day. In burn wounds, Group A showed lower contraction rate and lower healing rate on 7th and 14th day. Group C and D showed better healing on 21st day. This study demonstrates that the pH of Pectin/CMC dressing material is more important than absorption degree in fresh surgical and infected wound healing. However, absorption degree is more important than pH for burn wound healing.
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KEYWORD
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Bandages, Collagen, Pectin, Wound healing, Wound infection
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